Compound Q&A

How is (S)-5-(3-(tert-butylamino)-2-hydroxypropoxy)-3,4-dihydronaphthalen-1(2H)-one hydrochloride (CAS: 27912-14-7) typically synthesized?

Answer

(S)-5-(3-(tert-butylamino)-2-hydroxypropoxy)-3,4-dihydronaphthalen-1(2H)-one hydrochloride
The compound is typically synthesized via a multistep process involving the formation of a naphthalene derivative, introduction of the tert-butylamino group, and subsequent hydrolysis and chloride addition. This process requires careful control of pH and temperature to achieve high yields and selectivity. Commonly used reagents include tert-butylamine, sodium hydroxide, and hydrochloric acid.

About

CAS No 27912-14-7
English Name (S)-5-(3-(tert-butylamino)-2-hydroxypropoxy)-3,4-dihydronaphthalen-1(2H)-one hydrochloride
Molecular Formula C17H26ClNO3
Molecular Weight 327.85200000000003 g/mol
SMILES CC(C)(C)NCC(COC1=CC=CC2=C1CCCC2=O)O.Cl
InChIKey DNTDOBSIBZKFCP-YDALLXLXSA-N
Last Updated: 2025-11-05 07:29

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