Compound Q&A
How is 1-(1H-Indazol-5-yl)methanamine (CAS: 267413-25-2) typically synthesized?
Answer
1-(1H-Indazol-5-yl)methanamine (CAS: 267413-25-2) can be synthesized via the reaction of 5-bromoindazole with methylamine in the presence of a suitable base like sodium hydroxide. This method provides good selectivity and yields up to 90% of the desired product. Other methods involve the reduction of 5-bromomethylindazole using hydrogen and a palladium catalyst.
About
CAS No
267413-25-2
English Name
1-(1H-Indazol-5-yl)methanamine
Molecular Formula
C8H9N3
Molecular Weight
147.181 g/mol
SMILES
C1=CC2=C(C=C1CN)C=NN2
InChIKey
AQMGFFLBKVOJLW-UHFFFAOYSA-N
Last Updated: 2025-11-04 22:31
