Compound Q&A

How is 2-Methyl-2-propanyl (5-fluoro-1,3-thiazol-2-yl)carbamate (CAS: 731018-54-5) typically synthesized?

Answer

2-Methyl-2-propanyl (5-fluoro-1,3-thiazol-2-yl)carbamate
2-Methyl-2-propanyl (5-fluoro-1,3-thiazol-2-yl)carbamate is typically synthesized via a multi-step process involving the coupling of 5-fluoro-1,3-thiazol-2-yl isocyanate with 2-methyl-2-propanol. The reaction proceeds in the presence of a suitable catalyst, such as 4-dimethylaminopyridine (DMAP), with good selectivity and yield. The product is then purified by recrystallization from a suitable solvent.

About

English Name 2-Methyl-2-propanyl (5-fluoro-1,3-thiazol-2-yl)carbamate
Molecular Formula C8H11FN2O2S
Molecular Weight 218.253 g/mol
SMILES CC(C)(C)OC(=O)NC1=NC=C(S1)F
InChIKey VCMFSWGHVQKQGS-UHFFFAOYSA-N
Last Updated: 2025-11-04 13:04

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