Compound Q&A

How is (4-Bromo-2-pyridinyl)acetonitrile (CAS: 312325-73-8) typically synthesized?

Answer

(4-Bromo-2-pyridinyl)acetonitrile
(4-Bromo-2-pyridinyl)acetonitrile can be synthesized by reacting 2-bromopyridine with acetonitrile in the presence of a base like sodium hydride or potassium tert-butoxide. The reaction is typically carried out in an inert solvent such as dimethylformamide. The product is isolated by recrystallization from an appropriate solvent to obtain the crystalline form with high purity.

About

English Name (4-Bromo-2-pyridinyl)acetonitrile
Molecular Formula C7H5BrN2
Molecular Weight 17.031 g/mol
SMILES C1=CN=C(C=C1Br)CC#N
InChIKey PGQNQSWJQOUINY-UHFFFAOYSA-N
Last Updated: 2025-11-04 13:04

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