Compound Q&A

How is 3-Chloro-2-fluoroisonicotinic acid (CAS: 741683-19-2) typically synthesized?

Answer

3-Chloro-2-fluoroisonicotinic acid
3-Chloro-2-fluoroisonicotinic acid can be synthesized through the chlorination and fluorination of nicotinic acid. Commonly, this involves reacting nicotinic acid with chlorine and fluorine gases under controlled conditions. The reaction is typically catalyzed by anhydrous aluminum chloride and yields a high purity product with good selectivity and yield.

About

English Name 3-Chloro-2-fluoroisonicotinic acid
Molecular Formula C6H3ClFNO2
Molecular Weight 175.546 g/mol
SMILES C1=CN=C(C(=C1C(=O)O)Cl)F
InChIKey PYLURACOOBPBPM-UHFFFAOYSA-N
Last Updated: 2025-11-01 12:59

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