Compound Q&A
How is 1-Oxa-8-azaspiro[4.5]decan-3-one hydrochloride (CAS: 133382-42-0) typically synthesized?
Answer
![1-Oxa-8-azaspiro[4.5]decan-3-one hydrochloride (1:1)](https://static.chemtradehub.com/structs/133/133382-42-0-5a7f.webp "1-Oxa-8-azaspiro[4.5]decan-3-one hydrochloride (1:1)")
1-Oxa-8-azaspiro[4.5]decan-3-one hydrochloride is synthesized through a condensation reaction between 1-oxy-8-azaspiro[4.5]decanone and hydrochloric acid. Commonly, a mixture of the ketone and hydrochloric acid is heated to form the hydrochloride salt. The yield is typically around 90%, with good selectivity towards the 1:1 salt.
About
CAS No
133382-42-0
English Name
1-Oxa-8-azaspiro[4.5]decan-3-one hydrochloride (1:1)
Molecular Formula
C8H14ClNO2
Molecular Weight
191.658 g/mol
SMILES
C1CNCCC12CC(=O)CO2.Cl
InChIKey
FNDQRJDGTZYKAB-UHFFFAOYSA-N
Last Updated: 2025-10-31 17:33
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