Compound Q&A

How is 6-Chloro-1,2,3,4-tetrahydroquinoline (CAS: 49716-18-9) typically synthesized?

Answer

6-Chloro-1,2,3,4-tetrahydroquinoline
6-Chloro-1,2,3,4-tetrahydroquinoline is commonly synthesized via the condensation of chloroacetophenone with 1,2,3,4-tetrahydroquinoline. This reaction typically involves the use of a dehydrating agent and is carried out under acidic conditions. The product is isolated by recrystallization, yielding a high purity product with good selectivity and yield.

About

CAS No 49716-18-9
English Name 6-Chloro-1,2,3,4-tetrahydroquinoline
Molecular Formula C9H10ClN
Molecular Weight 167.63899999999998 g/mol
SMILES Clc1ccc2NCCCc2c1
InChIKey PASUADIMFGAUDB-UHFFFAOYSA-N
Last Updated: 2025-10-29 13:16

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