Compound Q&A
How is 4,4-dimethylpyrrolidin-2-one (CAS: 66899-02-3) typically synthesized?
Answer
4,4-Dimethylpyrrolidin-2-one can be synthesized via the oxidation of 4,4-dimethyl-1-pyrrolidinecarbinol using chromic acid or potassium permanganate. The reaction is typically carried out in aqueous solution, and the product can be isolated by filtration and recrystallization. It is also possible to synthesize it via the condensation of dimethyl malonate with methyl acrylate, followed by hydrolysis and dehydratation.
About
CAS No
66899-02-3
English Name
4,4-dimethylpyrrolidin-2-one
Molecular Formula
C6H11NO
Molecular Weight
113.15999999999998 g/mol
SMILES
CC1(CC(=O)NC1)C
InChIKey
HGVPKAGCVCGRDQ-UHFFFAOYSA-N
Last Updated: 2025-10-28 23:23
