Compound Q&A

How is (5-Nitro-2-pyridinyl)acetonitrile (CAS: 123846-66-2) typically synthesized?

Answer

(5-Nitro-2-pyridinyl)acetonitrile
(5-Nitro-2-pyridinyl)acetonitrile is commonly synthesized via the nitration of 2-pyridinylacetonitrile using concentrated nitric acid as the oxidizing agent. The reaction is carried out under reflux conditions, and the product is typically obtained with good selectivity and yield. Proper handling of nitric acid and other reagents is necessary to ensure safety and efficiency.

About

English Name (5-Nitro-2-pyridinyl)acetonitrile
Molecular Formula C7H5N3O2
Molecular Weight 163.13 g/mol
SMILES C1=CC(=NC=C1[N+](=O)[O-])CC#N
InChIKey PHCKNSBYAFTJKZ-UHFFFAOYSA-N
Last Updated: 2025-10-28 15:15

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