Compound Q&A
How is (3S)-3-(3-Fluorophenyl)-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)propanoic acid (CAS: 500770-72-9) typically synthesized?
Answer
![(3S)-3-(3-Fluorophenyl)-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)propanoic acid](https://static.chemtradehub.com/structs/500/500770-72-9-4b3b.webp "(3S)-3-(3-Fluorophenyl)-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)propanoic acid")
The compound is typically synthesized via a multistep process involving protection of the carboxylic acid group, formation of an ester, and substitution of a fluorophenyl group. Key reagents include fluorobenzoic acid, acyl chlorides, and esterification agents. The final step involves protecting group removal and isolation of the desired product. The overall yield is moderate, and the reaction is highly selective.
About
CAS No
500770-72-9
English Name
(3S)-3-(3-Fluorophenyl)-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)propanoic acid
Molecular Formula
C14H18FNO4
Molecular Weight
283.299 g/mol
SMILES
CC(C)(C)OC(=O)NC(CC(=O)O)C1=CC(=CC=C1)F
InChIKey
IQPQPXUDXQDVMK-NSHDSACASA-N
Last Updated: 2025-10-28 15:15
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