Compound Q&A

How is 5-Amino-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazole-4-carboxamide (CAS: 1082745-50-3) typically synthesized?

Answer

5-Amino-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazole-4-carboxamide
5-Amino-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazole-4-carboxamide is typically synthesized via a multistep process involving the condensation of an appropriate 1H-pyrazole-4-carboxamide with tetrahydro-2H-pyran-4-amine. The reaction is performed under basic conditions using a catalyst such as sodium hydride. The yield is generally around 70-80%, and the method is selective for the desired product.

About

English Name 5-Amino-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazole-4-carboxamide
Molecular Formula C9H14N4O2
Molecular Weight 210.23699999999997 g/mol
SMILES NC(=O)c1cnn(c1N)C1CCOCC1
InChIKey KKKDXSBBYUMEEQ-UHFFFAOYSA-N
Last Updated: 2025-10-28 10:54

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