Compound Q&A
How is N-alpha-Formyl-D-leucine (CAS: 44978-39-4) typically synthesized?
Answer
N-alpha-Formyl-D-leucine (CAS: 44978-39-4) is typically synthesized through the acylation of D-leucine with formic anhydride in the presence of a Lewis acid catalyst such as aluminum trichloride. The reaction yields a high level of selectivity and purity, with an overall yield of about 90%. This method is common in organic and peptide synthesis laboratories.
About
CAS No
44978-39-4
English Name
N-alpha-Formyl-D-leucine
Molecular Formula
C7H13NO3
Molecular Weight
159.18499999999997 g/mol
SMILES
CC(C)CC(C(=O)O)NC=O
InChIKey
HFBHOAHFRNLZGN-ZCFIWIBFSA-N
Last Updated: 2025-10-23 07:31
