Compound Q&A

How is 3-Phenyl-1,2-oxazol-5-amine (CAS: 4369-55-5) typically synthesized?

Answer

3-Phenyl-1,2-oxazol-5-amine
3-Phenyl-1,2-oxazol-5-amine is synthesized by the condensation of 5-aminooxazole with phenyl isothiocyanate. This reaction is typically conducted in the presence of a base such as pyridine. The yield of the product is around 75-80%, and the reaction is selective for the formation of the desired amine.

About

CAS No 4369-55-5
English Name 3-Phenyl-1,2-oxazol-5-amine
Molecular Formula C9H8N2O
Molecular Weight 160.17599999999996 g/mol
SMILES C1=CC=C(C=C1)C2=NOC(=C2)N
InChIKey HLOHVVZZMMMDMM-UHFFFAOYSA-N
Last Updated: 2025-10-22 19:24

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