Compound Q&A

How is 3-Fluoro-4-iodophenol (CAS: 122927-84-8) typically synthesized?

Answer

3-Fluoro-4-iodophenol
3-Fluoro-4-iodophenol (CAS: 122927-84-8) can be synthesized by the iodination of 3-fluorophenol using iodine and an acidic catalyst such as sulfuric acid. The reaction is carried out under reflux conditions, and the product is purified by recrystallization from ethanol. The yield is typically around 70-80%, with good selectivity towards the desired product.

About

English Name 3-Fluoro-4-iodophenol
Molecular Formula C6H4FIO
Molecular Weight 237.999 g/mol
SMILES C1=CC(=C(C=C1O)F)I
InChIKey CSQWLXZVUXRZFL-UHFFFAOYSA-N
Last Updated: 2025-10-22 12:37

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