Compound Q&A
How is 5-Formyl-2-thiophenecarboxylic acid (CAS: 4565-31-5) typically synthesized?
Answer
5-Formyl-2-thiophenecarboxylic acid is typically synthesized by the reaction of 2-thiophenecarboxylic acid with formic acid in the presence of a suitable catalyst, such as p-toluenesulfonic acid. The reaction involves esterification and the introduction of a formyl group, yielding a yield of around 75-85%. The product is purified by recrystallization from an appropriate solvent.
About
CAS No
4565-31-5
English Name
5-Formyl-2-thiophenecarboxylic acid
Molecular Formula
C6H4O3S
Molecular Weight
156.16199999999998 g/mol
SMILES
C1=C(SC(=C1)C(=O)O)C=O
InChIKey
VFEAMMGYJFFXKV-UHFFFAOYSA-N
Last Updated: 2025-10-20 00:35
