Compound Q&A

How is 5-Methyl-2-nitroaniline (CAS: 578-46-1) typically synthesized?

Answer

5-Methyl-2-nitroaniline
5-Methyl-2-nitroaniline (CAS: 578-46-1) is commonly synthesized by the reduction of 2-nitrobenzoyl chloride with methylamine. This process involves the use of aluminum chloride as a catalyst and typically yields 85-90% of the desired product. The reaction is carried out in a solvent such as methylene chloride at room temperature.

About

CAS No 578-46-1
English Name 5-Methyl-2-nitroaniline
Molecular Formula C7H8N2O2
Molecular Weight 152.15 g/mol
SMILES CC1=CC(=C(C=C1)[N+](=O)[O-])N
InChIKey IGDYNWKWXUCIJB-UHFFFAOYSA-N
Last Updated: 2025-10-20 00:35

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