Compound Q&A

How is (1R)-1-[4-(5-{[(1R)-6,7-Dimethoxy-2-methyl-1,2,3,4-tetrahydro-1-isoquinolinyl]methyl}-2-hydroxyphenoxy)benzyl]-7-methoxy-2-methyl-1,2,3,4-tetrahydro-6-isoquinolinol (CAS: 2831-75-6) typically synthesized?

Answer

(1R)-1-[4-(5-{[(1R)-6,7-Dimethoxy-2-methyl-1,2,3,4-tetrahydro-1-isoquinolinyl]methyl}-2-hydroxyphenoxy)benzyl]-7-methoxy-2-methyl-1,2,3,4-tetrahydro-6-isoquinolinol
This compound is typically synthesized via a multi-step process involving the coupling of an isoquinoline derivative with a benzyl halide, followed by subsequent modifications. The synthesis involves the use of standard organic synthesis techniques such as stirring, reflux, and recrystallization. The overall yield is moderate, and the reaction is selective under optimized conditions.

About

CAS No 2831-75-6
English Name (1R)-1-[4-(5-{[(1R)-6,7-Dimethoxy-2-methyl-1,2,3,4-tetrahydro-1-isoquinolinyl]methyl}-2-hydroxyphenoxy)benzyl]-7-methoxy-2-methyl-1,2,3,4-tetrahydro-6-isoquinolinol
Molecular Formula C37H42N2O6
Molecular Weight 610.7510000000001 g/mol
SMILES CN1CCC2=CC(=C(C=C2C1CC3=CC=C(C=C3)OC4=C(C=CC(=C4)CC5C6=CC(=C(C=C6CCN5C)OC)OC)O)OC)O
InChIKey APIHNXDZCYDPTF-FIRIVFDPSA-N
Last Updated: 2025-10-19 20:30

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