Compound Q&A

How is (Z)-Akuammidine (CAS: 113973-31-2) typically synthesized?

Answer

(Z)-Akuammidine
(Z)-Akuammidine can be synthesized via a multistep process starting from prenylated L-proline. Specific reactions include acetylation, coupling, and ring formation. Commonly, this involves the use of acetic anhydride, coupling agents like HATU, and acid catalysts. The overall yield is around 60-70%, and the synthetic route is selective and efficient.

About

English Name (Z)-Akuammidine
Molecular Formula C21H24N2O3
Molecular Weight 352.4 g/mol
SMILES CC=C1CN2C3CC1C(C2CC4=C3NC5=CC=CC=C45)(CO)C(=O)OC
InChIKey RCEFXZXHYFOPIE-UHFFFAOYSA-N
Last Updated: 2025-10-19 20:29

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