Compound Q&A

How is (2E)-2-Ethyl-4-(2,2,3-trimethyl-3-cyclopenten-1-yl)-2-buten-1-ol (CAS: 28219-61-6) typically synthesized?

Answer

(2E)-2-Ethyl-4-(2,2,3-trimethyl-3-cyclopenten-1-yl)-2-buten-1-ol
(2E)-2-Ethyl-4-(2,2,3-trimethyl-3-cyclopenten-1-yl)-2-buten-1-ol can be synthesized via a multistep process involving alkylation of a cationic intermediate. Commonly, the reaction is performed with a trimethylsilyl ether followed by deprotection with acid, yielding the desired alcohol. The overall yield is typically around 70%, and the reaction is selective with good regiochemical control.

About

CAS No 28219-61-6
English Name (2E)-2-Ethyl-4-(2,2,3-trimethyl-3-cyclopenten-1-yl)-2-buten-1-ol
Molecular Formula C14H24O
Molecular Weight 208.34499999999997 g/mol
SMILES CCC(=CCC1CC=C(C1(C)C)C)CO
InChIKey KHQDWCKZXLWDNM-KPKJPENVSA-N
Last Updated: 2025-10-17 07:35

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