Compound Q&A
How is 1,3,5-Tris(trifluoromethyl)benzene (CAS: 729-81-7) typically synthesized?
Answer
1,3,5-Tris(trifluoromethyl)benzene (CAS: 729-81-7) is typically synthesized via a Friedel-Crafts alkylation process. This involves the alkylation of toluene with trifluoromethyl triflate in the presence of aluminum chloride as a catalyst. The reaction provides high yield and selectivity, making this a common method for preparing this compound.
About
CAS No
729-81-7
English Name
1,3,5-Tris(trifluoromethyl)benzene
Molecular Formula
C9H3F9
Molecular Weight
282.1049999999999 g/mol
SMILES
C1=C(C=C(C=C1C(F)(F)F)C(F)(F)F)C(F)(F)F
InChIKey
ZMAUHKSOLPYPDB-UHFFFAOYSA-N
Last Updated: 2025-10-16 16:48
