Compound Q&A

How is 2,6-Naphthyridin-1(2H)-one (CAS: 80935-77-9) typically synthesized?

Answer

2,6-Naphthyridin-1(2H)-one
2,6-Naphthyridin-1(2H)-one can be synthesized via the condensation of 2-amino-6-nitrobenzaldehyde with acetic anhydride, followed by reduction of the nitro group. Alternatively, it can be produced by the dehydration of 2,6-diamino-1,3,5-triazine under acidic conditions. These methods yield pure compounds with high selectivity and good to excellent yields.

About

CAS No 80935-77-9
English Name 2,6-Naphthyridin-1(2H)-one
Molecular Formula C8H6N2O
Molecular Weight 146.149 g/mol
SMILES c1c[nH]c(=O)c2c1cncc2
InChIKey XVHNGLQDZFUCKO-UHFFFAOYSA-N
Last Updated: 2025-10-16 16:48

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