Compound Q&A
How is Boc-L-His(Bom)-OH (CAS: 79950-65-5) typically synthesized?
Answer
Boc-L-His(Bom)-OH is synthesized via solid-phase synthesis, which involves coupling L-His(Bom) to a Boc-protected amino acid. The synthesis typically uses HATU or DCM as a coupling reagent, with a yield of about 70-80%. The process is selective and yields a high-quality product suitable for further peptide synthesis.
About
CAS No
79950-65-5
English Name
Boc-L-His(Bom)-OH
Molecular Formula
C19H25N3O5
Molecular Weight
375.4250000000001 g/mol
SMILES
CC(C)(C)OC(=O)NC(CC1=CN=CN1COCC2=CC=CC=C2)C(=O)O
InChIKey
LPVKZCHCZSFTOJ-INIZCTEOSA-N
Last Updated: 2025-10-13 17:50
