Compound Q&A
How is N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-(3-thienyl)-D-alanine (CAS: 220497-90-5) typically synthesized?
Answer
![N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-(3-thienyl)-D-alanine](https://static.chemtradehub.com/structs/220/220497-90-5-9d73.webp "N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-(3-thienyl)-D-alanine")
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-(3-thienyl)-D-alanine (CAS: 220497-90-5) is usually synthesized via a multistep process involving coupling reactions, protecting group manipulations, and deprotection. Common methods include using coupling agents like HATU in the presence of a base such as DIPEA and protective groups like BOC (tert-butoxycarbonyl) for amine protection. The final product is obtained with high selectivity and yield.
About
CAS No
220497-90-5
English Name
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-(3-thienyl)-D-alanine
Molecular Formula
C22H19NO4S
Molecular Weight
393.4640000000001 g/mol
SMILES
C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NC(CC4=CSC=C4)C(=O)O
InChIKey
LSBZJMRHROCYGY-HXUWFJFHSA-N
Last Updated: 2025-10-13 17:50
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