Compound Q&A

How is 1-(4-Chlorophenyl)-2-cyclopropyl-1-propanone (CAS: 123989-29-7) typically synthesized?

Answer

1-(4-Chlorophenyl)-2-cyclopropyl-1-propanone
1-(4-Chlorophenyl)-2-cyclopropyl-1-propanone can be synthesized via a Claisen-Schmidt condensation between 4-chlorobenzaldehyde and cyclopropylmethyl ketone. The reaction is typically catalyzed by a base such as sodium hydroxide, and the product is isolated by recrystallization. The yield can be up to 80% with high selectivity.

About

English Name 1-(4-Chlorophenyl)-2-cyclopropyl-1-propanone
Molecular Formula C12H13ClO
Molecular Weight 208.68800000000002 g/mol
SMILES CC(C1CC1)C(=O)C2=CC=C(C=C2)Cl
InChIKey LRWCURGZPQWMRG-UHFFFAOYSA-N
Last Updated: 2025-10-13 12:55

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