Compound Q&A
How is Methyl 6-bromo-2-pyrazinecarboxylate (CAS: 40155-34-8) typically synthesized?
Answer
Methyl 6-bromo-2-pyrazinecarboxylate can be synthesized through the bromination of methyl 2-pyrazinecarboxylate using N-bromosuccinimide (NBS) in the presence of a radical initiator. This method provides good yield and selectivity for the bromo substituent at the 6-position. Common solvents include dichloromethane or acetonitrile.
About
CAS No
40155-34-8
English Name
Methyl 6-bromo-2-pyrazinecarboxylate
Molecular Formula
C6H5BrN2O2
Molecular Weight
217.022 g/mol
SMILES
COC(=O)c1cncc(Br)n1
InChIKey
LYNSTNYSMCKCSS-UHFFFAOYSA-N
Last Updated: 2025-10-10 21:10
