Compound Q&A
How is (11beta)-9-Fluoro-11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl acetate (CAS: 338-98-7) typically synthesized?
Answer
(11beta)-9-Fluoro-11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl acetate can be synthesized through a multi-step process involving the reduction of a suitable 17-ketosteroid, followed by fluoroalkylation and acetylation. Commonly used catalysts include palladium-based complexes. The synthesis typically yields up to 80% of the desired product, with good regioselectivity and excellent atom economy.
About
CAS No
338-98-7
English Name
(11beta)-9-Fluoro-11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl acetate
Molecular Formula
C23H29FO6
Molecular Weight
420.4770000000001 g/mol
SMILES
CC(=O)OCC(=O)C1(CCC2C1(CC(C3(C2CCC4=CC(=O)C=CC43C)F)O)C)O
InChIKey
ZOCUOMKMBMEYQV-GSLJADNHSA-N
Last Updated: 2025-10-10 13:51
