Compound Q&A
How is 4-{2-[4-(2-Methyl-2-propanyl)phenyl]ethoxy}quinazoline (CAS: 120928-09-8) typically synthesized?
Answer
![4-{2-[4-(2-Methyl-2-propanyl)phenyl]ethoxy}quinazoline](https://static.chemtradehub.com/structs/120/120928-09-8-d3db.webp "4-{2-[4-(2-Methyl-2-propanyl)phenyl]ethoxy}quinazoline")
4-{2-[4-(2-Methyl-2-propanyl)phenyl]ethoxy}quinazoline can be synthesized via a multi-step approach involving coupling reactions, acetylation, and quinazoline ring formation. Commonly, a protecting group strategy is used to control reactivity, and catalysts like palladium(II) acetate are employed to enhance selectivity and yield. The overall process involves careful temperature control and solvent selection to achieve high purity and yield.
About
CAS No
120928-09-8
English Name
4-{2-[4-(2-Methyl-2-propanyl)phenyl]ethoxy}quinazoline
Molecular Formula
C20H22N2O
Molecular Weight
306.40900000000005 g/mol
SMILES
CC(c1ccc(cc1)CCOc1ncnc2c1cccc2)(C)C
InChIKey
DMYHGDXADUDKCQ-UHFFFAOYSA-N
Last Updated: 2025-10-10 12:21
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