Compound Q&A
How is 1-(5-Bromo-2-fluorophenyl)ethanone (CAS: 198477-89-3) typically synthesized?
Answer
1-(5-Bromo-2-fluorophenyl)ethanone (CAS: 198477-89-3) can be synthesized by reacting 2-fluoro-5-bromophenol with ethyl chloroformate in the presence of an organic base like triethylamine. The reaction is typically carried out in a solvent such as dichloromethane. The yield is moderate, around 70-80%, with good regioselectivity towards the ethanone product.
About
CAS No
198477-89-3
English Name
1-(5-Bromo-2-fluorophenyl)ethanone
Molecular Formula
C8H6BrFO
Molecular Weight
217.03699999999998 g/mol
SMILES
CC(=O)C1=C(C=CC(=C1)Br)F
InChIKey
XNRQIHIOKXQSPG-UHFFFAOYSA-N
Last Updated: 2025-10-07 19:42
