Compound Q&A

How is Emtricitabine Menthyl Ester (CAS: 147126-75-8) typically synthesized?

Answer

Emtricitabine Menthyl Ester
Emtricitabine Menthyl Ester is synthesized through a multi-step process involving the menthyl esterification of emtricitabine. This typically involves the use of menthyl chloride in the presence of a base like sodium hydroxide. The reaction is carried out under mild conditions to achieve high selectivity and yield, with purification steps including recrystallization to obtain the final product.

About

English Name Emtricitabine Menthyl Ester
Molecular Formula C18H26FN3O4S
Molecular Weight 399.5 g/mol
SMILES CC1CCC(C(C1)OC(=O)C2OC(CS2)N3C=C(C(=NC3=O)N)F)C(C)C
InChIKey AUTCQXVTOIJYOT-UHFFFAOYSA-N
Last Updated: 2025-10-01 13:51

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