Compound Q&A

How is 2-Chloro-N-(hydroxymethyl)acetamide (CAS: 2832-19-1) typically synthesized?

Answer

2-Chloro-N-(hydroxymethyl)acetamide
2-Chloro-N-(hydroxymethyl)acetamide (CAS: 2832-19-1) is typically synthesized by the reaction of chloroacetic acid with methylamine or by the chlorination of N-(hydroxymethyl)acetamide. The reaction proceeds with good selectivity and yields can reach up to 90%. Catalysts such as sodium carbonate or potassium carbonate are often used to enhance the reaction efficiency.

About

CAS No 2832-19-1
English Name 2-Chloro-N-(hydroxymethyl)acetamide
Molecular Formula C3H6ClNO2
Molecular Weight 123.539 g/mol
SMILES C(C(=O)NCO)Cl
InChIKey TXNSZCSYBXHETP-UHFFFAOYSA-N
Last Updated: 2025-09-22 19:21

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