Compound Q&A

Are there alternatives to 4-Bromo-2,6-difluorobenzonitrile (CAS: 123843-67-4) in synthesis?

Answer

4-Bromo-2,6-difluorobenzonitrile
Yes, there are alternatives to 4-Bromo-2,6-difluorobenzonitrile (CAS: 123843-67-4) in synthesis. For example, 2,6-difluorobenzonitrile can be brominated using other halogenation agents. Common alternatives include using bromine in the presence of a Lewis acid catalyst or employing brominating reagents like N-bromosuccinimide (NBS) with radical initiators. These alternatives can provide similar functional groups but with varying reaction conditions and selectivities.

About

English Name 4-Bromo-2,6-difluorobenzonitrile
Molecular Formula C7H2BrF2N
Molecular Weight 207.01699999999997 g/mol
SMILES C1=C(C=C(C(=C1F)C#N)F)Br
InChIKey TZHQWUAOIWRFSW-UHFFFAOYSA-N
Last Updated: 2025-09-08 18:31

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