(+)-EPICATECHIN(CAS: 35323-91-2)

(2S,3S)-2-(3,4-Dihydroxyphenyl)-3,5,7-chromanetriol is a white crystalline solid with a molecular weight of approximately 328.22 g/mol. It is slightly soluble in water and has limited solubility in organic solvents. This compound is known for its high reactivity, particularly towards nucleophiles and reducing agents. It is stable under neutral and slightly basic conditions but is sensitive to strong acids and bases.

(2S,3S)-2-(3,4-Dihydroxyphenyl)-3,5,7-chromanetriol can be synthesized through a multi-step process involving the condensation of a 2-hydroxybenzaldehyde with a 3,4-dihydroxybenzyl alcohol followed by ring formation. The reaction typically employs a Lewis acid catalyst such as aluminum trichloride or zinc chloride. The process requires precise control of reaction conditions to ensure high selectivity and yield.

(2S,3S)-2-(3,4-Dihydroxyphenyl)-3,5,7-chromanetriol is used in the pharmaceutical industry for the preparation of certain active pharmaceutical ingredients. It also finds applications in the polymer industry for the synthesis of advanced materials with specific properties. Additionally, it is used in sensor technology for its unique chemical reactivity and in semiconductor manufacturing due to its electronic properties.

When handling (2S,3S)-2-(3,4-Dihydroxyphenyl)-3,5,7-chromanetriol, it is important to wear appropriate personal protective equipment (PPE), including gloves and safety glasses. The compound should be used in a well-ventilated area or a fume hood to minimize exposure. Spills should be cleaned up using appropriate absorbent materials, and the area should be thoroughly washed down. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information and emergency procedures.