(+/-)-ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID(CAS: 77521-29-0)

3-(5-Methyl-3-oxo-2,3-dihydro-1,2-oxazol-4-yl)alanine is a white crystalline solid with a molecular weight of approximately 182.23 g/mol. It has low solubility in water and is soluble in organic solvents. The compound is moderately reactive, particularly towards nucleophiles. It is stable under normal storage conditions but should be kept away from strong acids and bases.

3-(5-Methyl-3-oxo-2,3-dihydro-1,2-oxazol-4-yl)alanine can be synthesized via a multi-step process involving the condensation of 5-methyl-3-oxo-2,3-dihydro-1,2-oxazole with alanine. Commonly, this reaction is catalyzed by a suitable acid and performed in an appropriate solvent. The overall yield is typically around 70-80%, with excellent selectivity for the desired product.

3-(5-Methyl-3-oxo-2,3-dihydro-1,2-oxazol-4-yl)alanine is primarily used in the pharmaceutical industry for the synthesis of various drug candidates and intermediates. It also finds applications in the polymer industry as a monomer for producing functional polymers. Additionally, it is used in research for developing biosensors and in the semiconductor industry for certain applications.

When handling 3-(5-Methyl-3-oxo-2,3-dihydro-1,2-oxazol-4-yl)alanine, it is important to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area, preferably in a fume hood. Spills should be cleaned up immediately using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.