(1S)-1-(2-fluorophenyl)ethanamine;hydrochloride(CAS: 1332832-14-0)

(1S)-1-(2-Fluorophenyl)ethanamine hydrochloride is a white crystalline solid with a molecular weight of approximately 227.67 g/mol. It has a solubility of about 10 g/L in water and is slightly soluble in ethanol. The compound is basic and forms a stable salt with hydrochloric acid. It is less reactive than many other amines but can undergo nucleophilic substitution reactions under appropriate conditions.

(1S)-1-(2-Fluorophenyl)ethanamine hydrochloride is typically synthesized by reacting 2-fluorophenyl ethylamine with hydrochloric acid. The reaction is carried out in a solvent such as methanol or ethanol, and the product is isolated by recrystallization from a suitable solvent. The yield is generally high, and the reaction is selective and reproducible.

(1S)-1-(2-Fluorophenyl)ethanamine hydrochloride is used in the pharmaceutical industry as an intermediate in the synthesis of drugs. It is also utilized in the production of sensors and semiconductors due to its electronic properties. In polymer chemistry, it can serve as a monomer or additive.

Proper personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn when handling (1S)-1-(2-Fluorophenyl)ethanamine hydrochloride. The compound should be stored in a fume hood to minimize exposure. In the event of a spill, it should be immediately contained and treated according to the material safety data sheet (MSDS). Ensure proper ventilation and avoid inhaling the dust or vapor. This compound is not considered hazardous, but appropriate safety measures are essential for laboratory use.