3-Aminobenzenecarbothioamide(CAS: 78950-36-4)

3-Aminobenzenecarbothioamide (CAS: 78950-36-4) is a crystalline solid with a molecular weight of approximately 182.24 g/mol. It has a pKa of around 9.5 and is slightly soluble in water. It is relatively stable under normal conditions but can react with strong acids or bases. This compound is commonly used in pharmaceuticals and sensors.

3-Aminobenzenecarbothioamide (CAS: 78950-36-4) is often synthesized via the reaction of 3-aminobenzenethiol with carbonyl compounds. Common catalysts include palladium or other transition metals. The reaction involves the formation of an amide bond, typically yielding >90% purity. This method provides good selectivity and yield.

3-Aminobenzenecarbothioamide (CAS: 78950-36-4) is primarily used in the pharmaceutical and sensor industries. It serves as a precursor in the development of various drugs and is also employed in the fabrication of chemical sensors for detecting specific analytes.

When handling 3-Aminobenzenecarbothioamide (CAS: 78950-36-4), wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or fume hood to avoid inhalation. If a spill occurs, clean up using proper spill containment materials and follow safety data sheet (SDS) guidelines for disposal. Ensure proper ventilation and avoid contact with skin and eyes.