2-(2-Methylphenyl)acetyl Chloride(CAS: 10166-09-3)

2-(2-Methylphenyl)acetyl Chloride (CAS: 10166-09-3) is a colorless to white crystalline solid with a molecular weight of approximately 212.65 g/mol. It has a low solubility in water but is highly soluble in organic solvents such as dichloromethane and acetonitrile. This compound is known for its strong reactivity and ability to form esters and amides under certain conditions. It is used in organic synthesis and as a reagent in various chemical reactions.

2-(2-Methylphenyl)acetyl Chloride is typically synthesized by the reaction of 2-methylbenzaldehyde with acetyl chloride in the presence of an acid catalyst, such as concentrated hydrochloric acid. The process involves condensation followed by chlorination. The yield is generally high, and the reaction is selective, making it a reliable method for preparing this compound.

2-(2-Methylphenyl)acetyl Chloride (CAS: 10166-09-3) is primarily used in the pharmaceutical and polymer industries. It serves as a key intermediate in the synthesis of various drugs and polymers. Additionally, it finds applications in the production of sensors and semiconductors due to its reactivity and stability.

When handling 2-(2-Methylphenyl)acetyl Chloride (CAS: 10166-09-3), safety is paramount. Always wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work in a well-ventilated fume hood or under a biological safety cabinet. Spills should be cleaned up immediately using absorbent materials, and the area should be properly decontaminated. Refer to the Safety Data Sheet (SDS) for detailed emergency procedures and disposal methods.