Cefotiam Hexetil Hydrochloride(CAS: 95789-30-3)

Cefotiam Hexetil Hydrochloride is a crystalline compound with a molecular weight of approximately 534.8 g/mol. It has a melting point of 240-243°C and is sparingly soluble in water. Its hydrochloride form increases its solubility in aqueous solutions. This compound is relatively chemically stable but may undergo hydrolysis in basic conditions. It is used in the pharmaceutical industry for its antibiotic properties.

Cefotiam Hexetil Hydrochloride is synthesized by the esterification of cefotiam acid with hexetil alcohol, followed by the addition of hydrochloric acid to form the hydrochloride salt. Commonly, this reaction is carried out under mild conditions to ensure high selectivity and yield. The process involves careful control of pH and temperature to optimize product formation.

Cefotiam Hexetil Hydrochloride primarily finds application in the pharmaceutical industry as an antibiotic. It is used in the formulation of medications for the treatment of various bacterial infections. Although it has limited use in other industries, it may be explored for its potential in biosensors and other medical applications.

When handling Cefotiam Hexetil Hydrochloride, it is important to wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure. Spills should be cleaned up immediately using appropriate absorbent materials. Always refer to the safety data sheet (SDS) for detailed handling instructions and emergency procedures.