3-O-Acetyloleanolic Acid(CAS: 4339-72-4)

3-O-Acetyloleanolic Acid is a colorless crystalline solid with a molecular weight of approximately 512.62 g/mol. It is poorly soluble in water but soluble in ethanol and methanol. Chemically, it is less reactive than its parent compound, oleanolic acid, due to the acetylation at the 3-position. It has a melting point of around 170-172°C and exhibits good stability under normal storage conditions.

3-O-Acetyloleanolic Acid is typically synthesized through the acetylation of oleanolic acid with acetic anhydride in the presence of a strong acid catalyst, such as sulfuric acid. The reaction is carried out at a temperature of 100-110°C. The product is purified by recrystallization from ethanol, yielding a high purity of the compound with good yield and selectivity.

3-O-Acetyloleanolic Acid is mainly used in the pharmaceutical industry for the development of bioactive compounds. It also finds applications in the cosmetic industry as a skin care ingredient. Additionally, it is used in the production of functional foods and nutraceuticals for its health-promoting properties. In specialized industries, it might be utilized in the preparation of certain polymers and as a starting material for the synthesis of other natural product derivatives.

When handling 3-O-Acetyloleanolic Acid, it is important to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. This compound should be stored in a well-ventilated area and away from heat sources. In case of a spill, it should be carefully cleaned up using appropriate absorbent materials. The material safety data sheet (MSDS) should always be consulted for detailed safety information and emergency procedures. Handling should be done under a fume hood to minimize inhalation exposure.