Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate(CAS: 82419-34-9)

Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate is a crystalline compound with a molecular weight of approximately 318.08 g/mol. It has a low solubility in water but is soluble in organic solvents like methanol and dichloromethane. The compound is reactive towards nucleophiles, demonstrating electrophilic aromatic substitution properties. It exhibits moderate stability under normal laboratory conditions but requires protection from moisture and air.

Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate can be synthesized via a multistep procedure involving the protection of a primary alcohol, subsequent ring formation, and derivatization with fluoro and methyl groups. Typically, the reaction is performed using standard organic synthesis techniques with appropriate solvents and catalysts to achieve high selectivity and yield.

Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate finds applications in pharmaceuticals, where it may serve as an intermediate in the synthesis of more complex molecules. It is also relevant in the development of new materials, particularly in the fields of polymers and sensors, due to its unique chemical properties.

When handling Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated fume hood to minimize inhalation risks. Spills should be handled with caution, using absorbent materials to contain the spill and dispose of according to local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling and emergency procedures.