2-Hydroxy(~2~H_4_)benzoic acid(CAS: 78646-17-0)

2-Hydroxy(2H-4-)benzoic acid is a crystalline compound with a molecular weight of approximately 146.12 g/mol. It is soluble in water and ethanol. Chemically, it exhibits typical carboxylic acid reactivity, such as esterification and neutralization. It also shows acidity, with a pKa of about 4.29.

2-Hydroxy(2H-4-)benzoic acid can be synthesized by the reduction of 2-benzoyl-1,3-dihydro-2H-indol-2-one using hydrogen gas over a palladium catalyst. The reaction yields the target compound with high selectivity and good yield under mild conditions.

2-Hydroxy(2H-4-)benzoic acid is used in the pharmaceutical industry for the synthesis of certain drugs. It also finds application in the polymer industry as a stabilizer, and in the sensor industry for its use as a sensing material. Additionally, it is utilized in the semiconductor industry as an intermediate in the production of organic semiconductors.

When handling 2-Hydroxy(2H-4-)benzoic acid, ensure proper Personal Protective Equipment (PPE) including gloves, goggles, and lab coat. Store it in a fume hood to avoid inhaling dusts. In case of spill, use appropriate absorbent materials to contain the spill, then clean up according to the Safety Data Sheet (SDS). Always follow the recommended safety guidelines and consult the SDS for detailed information.