4,6-Diphenyl-1,3,5-triazin-2(1H)-one(CAS: 1917-44-8)

4,6-Diphenyl-1,3,5-triazin-2(1H)-one is a crystalline solid with a molecular weight of approximately 280.26 g/mol. It has limited water solubility and good solubility in organic solvents such as dimethyl sulfoxide (DMSO) and dimethylformamide (DMF). Chemically, it is characterized by its high stability and moderate reactivity, particularly in nucleophilic substitution reactions.

4,6-Diphenyl-1,3,5-triazin-2(1H)-one is commonly synthesized via the Stetter reaction, which involves the condensation of 2,4-diamino-6-phenyl-1,3,5-triazine with phenylacetonitrile. This method provides good yields and high selectivity, often without the need for additional catalysts.

4,6-Diphenyl-1,3,5-triazin-2(1H)-one is primarily used in the pharmaceutical industry for its role in drug synthesis, particularly in the development of antiviral and antifungal agents. It also finds applications in the polymer industry as a stabilizer and in the electronics industry for its use in sensors and semiconductor materials.

When handling 4,6-Diphenyl-1,3,5-triazin-2(1H)-one, it is important to wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and a laboratory coat. Work should be conducted in a well-ventilated hood to minimize exposure. In case of spillage, immediately clean up using appropriate absorbent materials and ensure proper disposal. Always consult the Safety Data Sheet (SDS) for detailed emergency procedures.