Oxazole, 5-(4-chlorophenyl)-(CAS: 1008-94-2)

5-(4-Chlorophenyl) oxazole (CAS: 1008-94-2) is a crystalline compound with a molecular weight of approximately 199.0 g/mol. It has a high solubility in organic solvents like dichloromethane and acetone. This compound is moderately reactive, particularly with nucleophiles. It is stable under normal conditions but should be stored away from strong oxidizing agents and acids.

5-(4-Chlorophenyl) oxazole (CAS: 1008-94-2) is commonly synthesized through a condensation reaction between 4-chlorophenyl isothiocyanate and hydroxylamine. The reaction is typically carried out in the presence of a Lewis acid catalyst, such as aluminum chloride, leading to a high yield of the desired product.

5-(4-Chlorophenyl) oxazole (CAS: 1008-94-2) is used in various industries, particularly in pharmaceuticals for its potential as a precursor in drug synthesis. It also finds applications in the production of polymers, sensors, and semiconductors due to its unique chemical properties.

When handling 5-(4-Chlorophenyl) oxazole (CAS: 1008-94-2), it is essential to wear appropriate personal protective equipment, including gloves and safety goggles. Work should be conducted in a well-ventilated area or a fume hood. In case of a spill, use a spill kit and follow safety data sheet (SDS) guidelines for proper disposal. Storage should be in a cool, dry place away from heat sources and oxidizing agents.