(4aS,7aR)-Octahydro-1H-pyrrolo[3,4-b]pyridine(CAS: 158060-81-2)

(4aS,7aR)-Octahydro-1H-pyrrolo[3,4-b]pyridine is a crystalline solid with a molecular weight of approximately 117.14 g/mol. It has limited water solubility but is more soluble in organic solvents. It exhibits basic properties due to its pyridine ring. The compound is stable under normal conditions but can react with strong acids or bases. It is not flammable but should be handled in a fume hood to avoid inhalation and contact with skin.

(4aS,7aR)-Octahydro-1H-pyrrolo[3,4-b]pyridine can be synthesized via reduction of 2,3-dihydro-1H-pyrrolo[3,4-b]pyridine with a suitable reducing agent such as sodium borohydride in an alcohol solvent. This process yields high purity product with good selectivity and moderate to high yield. The reaction should be conducted under an inert atmosphere to prevent oxidation.

(4aS,7aR)-Octahydro-1H-pyrrolo[3,4-b]pyridine has applications in pharmaceuticals, where it is used as a precursor for certain drugs. It is also utilized in the synthesis of polymers for their electronic properties, and as a component in sensors and semiconductors due to its electronic characteristics.

When handling (4aS,7aR)-Octahydro-1H-pyrrolo[3,4-b]pyridine, it is essential to wear appropriate personal protective equipment (PPE) such as gloves and goggles. The material should be used in a well-ventilated area or a fume hood to avoid inhalation. Spills should be cleaned up promptly using appropriate absorbent materials, and the area should be ventilated to remove any vapors. Always refer to the Safety Data Sheet (SDS) for detailed handling instructions and emergency procedures.