4-Bromo-1H-indole-3-carbaldehyde(CAS: 98600-34-1)

4-Bromo-1H-indole-3-carbaldehyde (CAS: 98600-34-1) is a crystalline solid with a molecular weight of approximately 211.04 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and dichloromethane. This compound exhibits moderate reactivity, particularly towards nucleophiles and reducing agents. It is a key intermediate in organic synthesis, known for its stability under various reaction conditions.

4-Bromo-1H-indole-3-carbaldehyde (CAS: 98600-34-1) can be synthesized via the bromination of indole-3-carbaldehyde. This process involves the use of bromine in the presence of a Lewis acid catalyst, such as aluminum bromide. The reaction is typically performed in aprotic solvents like dichloromethane or ethylene dichloride, under anhydrous conditions to ensure high yield and selectivity.

4-Bromo-1H-indole-3-carbaldehyde (CAS: 98600-34-1) is primarily used in the pharmaceutical and fine chemical industries as a precursor for the synthesis of complex organic molecules. It is also of interest in the polymer industry for developing new materials with specific functional groups. Additionally, this compound can be used in the development of sensors and semiconductor materials for its unique reactivity and structural properties.

When handling 4-Bromo-1H-indole-3-carbaldehyde (CAS: 98600-34-1), it is crucial to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure to bromine and other reactive species. Spills should be cleaned up immediately using appropriate absorbent materials and waste should be disposed of according to local regulations. Always refer to the safety data sheet (SDS) for detailed handling instructions and emergency response procedures.