(16beta)-21-Chloro-9-fluoro-17-hydroxy-16-methylpregna-1,4-diene-3,11,20-trione(CAS: 54063-32-0)

(16beta)-21-Chloro-9-fluoro-17-hydroxy-16-methylpregna-1,4-diene-3,11,20-trione is a crystalline compound with a molecular weight of approximately 519.78 g/mol. It has low water solubility and is poorly soluble in water. The compound is reactive, particularly towards nucleophiles and can undergo hydrolysis under basic conditions. It is stable under normal storage conditions but reacts with bases and oxidizing agents.

(16beta)-21-Chloro-9-fluoro-17-hydroxy-16-methylpregna-1,4-diene-3,11,20-trione is synthesized through a complex multi-step process involving the modification of steroid precursors. Common synthetic routes include stereoselective reductions, chlorination, fluorination, and hydroxylation reactions. Catalysts such as palladium or platinum complexes are often used to achieve high selectivity and yield.

(16beta)-21-Chloro-9-fluoro-17-hydroxy-16-methylpregna-1,4-diene-3,11,20-trione is primarily used in the pharmaceutical industry for the development of new drugs. It may also find applications in research and development for hormone-related therapies and in the synthesis of other bioactive compounds.

When handling (16beta)-21-Chloro-9-fluoro-17-hydroxy-16-methylpregna-1,4-diene-3,11,20-trione, ensure the use of appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize exposure. Spills should be cleaned up using appropriate absorbents and the area thoroughly decontaminated. Always refer to the safety data sheet (SDS) for detailed handling and disposal instructions.