2-{2-[2-(Benzyloxy)ethoxy]ethoxy}ethanamine(CAS: 86770-75-4)

2-{2-[2-(Benzyloxy)ethoxy]ethoxy}ethanamine (CAS: 86770-75-4) is a colorless or white crystalline solid with a molecular weight of approximately 354.38 g/mol. It has a low melting point around 45-47°C and a pKa value of about 10.4. The compound is slightly soluble in water but miscible with organic solvents like methanol and ethanol. Chemically, it is stable under neutral conditions but can undergo hydrolysis in acidic or basic media.

2-{2-[2-(Benzyloxy)ethoxy]ethoxy}ethanamine (CAS: 86770-75-4) is typically synthesized via a multi-step process involving the first protection of ethanamine with benzyl chloride, followed by the introduction of the ethoxy groups. This synthesis often requires the use of a catalyst such as sodium hydride and is carried out in a polar aprotic solvent like dimethylformamide (DMF). The yield is usually around 65-75%, with high selectivity for the target product.

2-{2-[2-(Benzyloxy)ethoxy]ethoxy}ethanamine (CAS: 86770-75-4) is primarily used in the pharmaceutical industry for the synthesis of certain drug intermediates. It also finds applications in the polymer industry as a modifier or stabilizer, and in the sensor industry for developing gas-sensing materials. Additionally, it is used in the semiconductor industry as a chemical vapor deposition (CVD) precursor.

When handling 2-{2-[2-(Benzyloxy)ethoxy]ethoxy}ethanamine (CAS: 86770-75-4), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be handled in a well-ventilated area or a fume hood to avoid inhalation risks. Spills should be cleaned up carefully using absorbent materials and proper disposal methods. The Material Safety Data Sheet (MSDS) and safety data sheet (SDS) should be consulted for detailed handling and emergency procedures.