2-Amino-1,3-oxazole-5-carboxylic acid(CAS: 881637-11-2)

2-Amino-1,3-oxazole-5-carboxylic acid (CAS: 881637-11-2) is a white to off-white crystalline solid. It has a molecular weight of approximately 167.17 g/mol and a solubility in water of 1.96 g/L at 25°C. This compound is moderately reactive, particularly with bases and certain nucleophiles. It can form salts and esters, and has been used in synthesis as a versatile building block.

2-Amino-1,3-oxazole-5-carboxylic acid (CAS: 881637-11-2) can be synthesized via the condensation of oxalic acid with aniline. Alternatively, it can be prepared from the reaction of 5-amino-1,3-oxazole with acetic anhydride. The yield is typically around 70-80%, and the reaction is performed under mild conditions, often in the presence of a catalyst such as pyridine.

2-Amino-1,3-oxazole-5-carboxylic acid (CAS: 881637-11-2) is used in the pharmaceutical industry as an intermediate for the synthesis of various drugs. It is also used in polymer chemistry for the preparation of functionalized polymers, in sensor technology for the development of chemical sensors, and in semiconductor applications as a precursor for thin film deposition processes.

When handling 2-Amino-1,3-oxazole-5-carboxylic acid (CAS: 881637-11-2), wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and a lab coat. Work in a well-ventilated area or fume hood to avoid inhalation of dust or aerosols. Handle spills with appropriate absorbent materials and dispose of according to local regulations. Always consult the safety data sheet (SDS) for specific handling and disposal instructions.