ent-3-Methoxy-17-methylmorphinan-10-one(CAS: 57969-05-8)

ent-3-Methoxy-17-methylmorphinan-10-one (CAS: 57969-05-8) has a crystalline form and a molecular weight of approximately 298.37 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and methanol. This compound is less reactive under normal conditions but can undergo mild acid catalysis to form related derivatives. It's important to handle this compound under protective measures to prevent degradation.

ent-3-Methoxy-17-methylmorphinan-10-one is typically synthesized through a multi-step process involving the protection of the morphinan ring, introduction of the methoxy group, and subsequent derivatization. Commonly used catalysts include Lewis acids, and the overall yield can range from 50% to 70%. Detailed synthetic methodology and conditions can be found in various organic chemistry literature.

ent-3-Methoxy-17-methylmorphinan-10-one (CAS: 57969-05-8) is primarily used in the pharmaceutical industry for the development of novel analgesics and antitussives. It also finds applications in the research of opioid receptor modulation. This compound may be explored in the polymer and sensor industries for specific applications, though its primary focus remains in pharmaceutical research and development.

When handling ent-3-Methoxy-17-methylmorphinan-10-one (CAS: 57969-05-8), it is crucial to wear appropriate personal protective equipment (PPE), including gloves and lab coat. Work should be conducted in a fume hood to minimize inhalation risks. Spills should be handled using appropriate clean-up procedures and materials. Refer to the safety data sheet (SDS) for detailed instructions and emergency procedures. Always ensure good ventilation in the laboratory setting.