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2-(4-Aminophenylthio)acetic Acid(CAS: 104-18-7)

2-(4-Aminophenylthio)acetic Acid
CAS Number

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Basic Information

Molecular Formula
C8H9NO2S
Molecular Weight
183.23 g/mol

Physical Properties

Melting Point
197-203 °C
Boiling Point
405.3°Cat760mmHg
Density
1.35
Flash Point
198.9°C

Chemical Identifiers

SMILES
C1=CC(=CC=C1N)SCC(=O)O
InChIKey
CTPIHHXCACYCIV-UHFFFAOYSA-N

Database References

MDL Number
MFCD00025360
Beilstein Registry Number
2720454

FAQ

2-(4-Aminophenylthio)acetic Acid (CAS: 104-18-7) is a white to light yellow crystalline solid. It has a molecular weight of approximately 194.23 g/mol and a molar mass of 194.23 g/mol. The compound is slightly soluble in water and has good solubility in organic solvents like methanol and ethanol. It is reactive towards bases and can undergo nucleophilic substitution reactions. It decomposes above 150°C.
2-(4-Aminophenylthio)acetic Acid (CAS: 104-18-7) is typically synthesized through the reaction of 2-(4-hydroxyphenylthio)acetic acid with sodium hydride in an anhydrous solvent like dimethylformamide (DMF). The reaction yields the amine derivative with high selectivity and good yield. This process requires proper handling of bases and solvents.
2-(4-Aminophenylthio)acetic Acid (CAS: 104-18-7) is used in the pharmaceutical industry for the synthesis of various drugs, particularly those requiring thioether functionalities. It is also utilized in the polymer industry for the modification of polymer properties and in sensor technology for its capability to bind specific analytes.
When handling 2-(4-Aminophenylthio)acetic Acid (CAS: 104-18-7), it is important to wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated fume hood due to its potential for volatilization. Spills should be cleaned up with caution using appropriate absorbents, and the area should be ventilated. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.

Safety Notice

Please verify product specifications and safety data before use. Contact the supplier for detailed safety information.

Always follow proper handling procedures

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