4-Oxo-1,4-dihydro-8-quinolinecarbonitrile(CAS: 848128-91-6)

4-Oxo-1,4-dihydro-8-quinolinecarbonitrile is a crystalline solid with a molecular weight of approximately 214.22 g/mol. It has a low solubility in water but is more soluble in organic solvents like dichloromethane and acetonitrile. It exhibits good stability under normal conditions but can react with strong bases. This compound is often used in synthetic chemistry due to its reactivity.

4-Oxo-1,4-dihydro-8-quinolinecarbonitrile is typically synthesized via a multi-step route involving the alkylation of quinoline followed by nitrile formation. Commonly, this involves the use of acetonitrile in the presence of a suitable catalyst like palladium or a Lewis acid. The reaction is carried out under mild conditions to achieve high selectivity and yield.

4-Oxo-1,4-dihydro-8-quinolinecarbonitrile is primarily used in the pharmaceutical and polymer industries. It serves as a building block for the synthesis of various medicinal compounds and can also be used in the production of functional polymer materials due to its unique structural properties.

When handling 4-Oxo-1,4-dihydro-8-quinolinecarbonitrile, it is important to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. The compound should be handled in a well-ventilated area or within a fume hood. In case of a spill, it is recommended to clean up using appropriate absorbent materials and to follow the safety data sheet (SDS) guidelines. Ensure proper disposal methods are followed to prevent environmental contamination.